In what dimension do you mean? Legally? Yes, unless based out of a place with an anti-BDS law. Politically? Sure, it's a bet against those currently in power and for the sentiment in the population. Practically? Yes, they can refuse business and contracts. I suppose they could also put killswitches in their hardware/software, but I wouldn't be a fan of that for digital-rights reasons. Economically? Who knows, the market makes no sense at all currently. They could probably get away with whatever.