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Re:Why Has There Been So Little Progress on Alzheimer's Dise... by ifwinterco on Sunday April 26, 2026 @04:22AM (#47908457)
Huge codebase with years of fixes, features and hacks added on top and nothing ever refactored.

It’s a miracle it works at all

Re:Why Has There Been So Little Progress on Alzheimer's Dise... by generic92034 on Sunday April 26, 2026 @05:39AM (#47908866)
It is worse. The code changes are mostly random, only surviving the tests of fitness nature is applying (on various levels though; immediately catastrophic changes on level of cell biology are sorted out). And at least the high-level tests are also random and unreliable.
Re:Why Has There Been So Little Progress on Alzheimer's Dise... by ravenstine on Sunday April 26, 2026 @06:35AM (#47909140)
So basically it's a codebase mostly composed of bugs, and the features mysteriously work because they're based on bugs that happen to be mitigated by other bugs. :)
Re:Why Has There Been So Little Progress on Alzheimer's Dise... by D-Coder on Sunday April 26, 2026 @02:00PM (#47912363)
A billion years of kludges.