Not a business use case, but I run it for my home server. I've got some QNAP JBOD SAS enclosures that only support firmware updates via Windows (or QNAP NAS). Every other disk enclosure I looked at involved some compromises (e.g. rackmounted, or non-SAS, or a custom-built thing that I'm not really interested in.)

The next best alterative would be a Mac Studio with Thunderbolt enclosures, but that would be notably more expensive, and macOS isn't great as a server OS.