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Re:Ah, peptides. where to begin? by XorNot on Tuesday April 07, 2026 @03:02AM (#47671644)
It is not ineffective outside of clinical trials. All the evidence says that people gain some weight back after they discontinue treatment - which is not a lack of efficacy. But they also usually gain back less then they lost.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12361690/

Re:Ah, peptides. where to begin? by rzmmm on Tuesday April 07, 2026 @03:41AM (#47671925)
It's kind of two separate topics: 1. Whether patients can adhere to GLP1. 2. Whether discontinuation leads to weight regain.