Almost exactly, it's mostly how you use the REPL that differs, and then only because of what different editors prioritise. When I'm in Emacs, all my work happens against a running REPL - when I open or save a file, it's reloaded. Any tests loaded in the REPL rerun on every save, within that live instance. If I drop into the debugger, it's against that live instance. I can swap in mock components to a running system, go check stuff in a browser (even jack into a live webpage with ClojureScript), all in one long running instance. I have struggled to recreate this kind of setup as smoothly in Python with any editor (pytest doesn't want to run this way, and IPython's autoreload doesn't feel as reliable), but I do probably write more REPLy code in Python than most, so all my model training and optimisation runs during development happen in pausable background threads in IPython etc.

All that said, 90% of the time you still just eval a bit of a code to see what happens and that's the same between the two languages.