If you mean that you can infer client side tampering with the page contents you could still do that - permit typing but don't permit the submit action on the client. The user presses enter but nothing happens until the check is complete. There you go, now you can tell if the page was tampered with (not that it makes much difference tbh).
(Separately, I don't think the article has adequately demonstrated this claim. They just make the claim in the title. The actual article only shows that some network request is made, and that the request happens after the React app is loaded, but not that they prevent input until it returns. Maybe it's obvious from using it, but they didn't demonstrate it.)
Blocking until load means that human interaction is physically impossible, so you are certain that any input before that is automated.
If you allow typing, this distinction vanishes
The reason it has to block until it's loaded is that otherwise the signal being missing doesn't imply automation. The user might have just typed before it loaded. If you know a legit user will always deliver the data, you can use the absence of it to infer something about what's happening on the client. You can obviously track metrics like "key event occurred before bot detection script did" without using it as an automation signal, just for monitoring.