From Wikipedia:
...Methamphetamine has a high potential for abuse and addiction, activating the psychological reward system by triggering a cascading release of dopamine in the brain characterized by Amphetamine /Stimulant psychosis.
Chronic abuse may also lead to post-withdrawal syndrome, a result of methamphetamine-induced neurotoxicity to dopaminergic neurons. Post-withdrawal syndrome can persist beyond the withdrawal period for months, and sometimes up to a year...
Got some junkie friends? I know a couple of them, burned and miserable lives mostly. On the other hand, all my drinking friends are quite normal, no addictions, no suffering from alcohol.
This comment is making me realize that I have a lot of fucked up friends.
Anyway, I'm fighting an anecdote with an anecdote but the most harmful thing about addiction is getting thrown in jail, getting jail marked down on your permanent record, being afraid to ask for help (or help being unavailable) because Johnny Law is getting tough on crime. The substance doesn't matter.