> I think the solution in harder-to-verify cases is to provide AI (sub-)agents a really good set of instructions on a detailed set of guidelines of what it should do and in what ways it should think and explore and break down problems
Using LLMs to validate LLMs isn't a solution to this problem. If the system can't self-verify then there's no signal to tell the LLM that it's wrong. The LLM is fundamentally unreliable, that's why you need a self-verifying system to guide and constrain the token generation.
For the easy-to-verify fields like coding, you can train "domain intuitions" directly to the LLM (and some of this training should generalize to other knowledge work abilities), but for other fields you would need to supply them in the prompt as the abilities cannot be trained into the LLM directly. This will need better models but might become doable in a few generations.