What is moderation? The volume (or mass) of a single apple of alcohol is going to make you very drunk (most alcohol is mixed with water: an apple's worth of beer is very little, that much Everclear is a problem).

That is what I hate about the everything in moderation. We need to do better since some things should be in much larger amounts than others.

I think we all would agree that any amount of rat poison is a bad thing, thought perhaps this is too much of a strawman.