Why impose such a limitation on your system when you don't have to by using some other database actually designed for multi user systems (Postgres, MySQL, etc)?
Assuming you can accept 99% uptime (that's ~3 days a year being down), and if you were on a single cloud in 2025; that's basically last year.
We need not assume internet FB level scale for typical biz apps where one instance may support a few hundred users max. Or even few thousand. Over engineering under such assumptions is likely cost ineffective and may even increase surface area of risk. $0.02
Most will want to use a managed db, but for a real basic setup you can just run postgres or mysql on the same box. And running your own db on a separate VPS is not hard either.
Turns out a lot when you have things like "last accessed" timestamps on your models.
Really depends on the app
I also don't think that calculation is valid. Your users aren't going to be purely uniformly accessing the app over the course of a day. Invariably you'll have queuing delays above a significantly smaller user count (but maybe the delays are acceptable)
If your writes are fast, doing them serially does not cause anyone to wait.
How often does the typical user write to the DB? Often it is like once per day or so (for example on hacker news). Say the write takes 1/1000s. Then you can serve
And nobody has to wait longer than a second when they hit the "reply" button, as I do now ...