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A comment on HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark. Parent comment

Re:HPV vaccination reduces oncogenic HPV16/18 prevalence fro... by LorenPechtel on Friday January 02, 2026 @08:34PM (#46471832)
The age 45 bit isn't actually a guideline. Rather, finding naive but at risk individuals over 45 is quite difficult. They did not test it on anyone over 45, thus the FDA approval cuts off at 45.
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Re:HPV vaccination reduces oncogenic HPV16/18 prevalence fro... by timr on Friday January 02, 2026 @10:42PM (#46472577)
That’s definitely true, but if you look at the RCT data, there’s also a question of efficacy in older recipients.

For whatever reason the vaccine just doesn’t seem to work as well when administered to adults, even if they’re naive to the viruses.

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