News for hackers. Stuff that matters.
Re:Show HN: CatalystAlert – Free biotech catalyst calendar (... by nykodev on Monday December 08, 2025 @01:38AM (#46189133)
Last year I panic-sold my biotech positions after missing two PDUFA dates in the same week. Both drugs got rejected. I was using a free tracker that hadn't been updated in months.

So I looked at what's available:

→ BioPharmCatalyst: $30-50/month → Free alternatives: clunky UIs from 2010, outdated data, broken filters → Finviz/Yahoo: no catalyst-specific tracking

I built CatalystAlert to fix this.

What it tracks: → 985 biotech companies, 1714 drugs in pipeline → PDUFA dates, Phase 1/2/3 readouts, AdCom meetings → Data pulled daily from ClinicalTrials.gov, SEC EDGAR, FDA

Stack: Next.js, Python data pipeline, daily automated scraping.

No account required, no paywall, no "unlock premium to see this date."

The core stays free. I'm prototyping V2 with ML-based approval probability predictions (trained on historical FDA decisions + trial endpoints) – that might have a paid tier eventually, but the calendar never will.

Feedback I'd love: 1. Data sources I'm missing? 2. Filters or views that would save you time? 3. Anything broken or confusing?

Thanks for checking it out.

There are no comments on this comment yet.