I suppose it depends on your definition of worse. It is more versatile. It's also toxic and fragile, and far more likely to break in ways that are hard to repair. I can only think of one object I own where the physical properties of particle board or MDF are a positive: a subwoofer where its consistency helps with acoustics.

It helps with all types of speakers, not just subwoofers. For the same reasons, it can work as structural parts of furniture.