Great question, cause I am in the same boat. One thing I was looking into was "Startup Visa", more info here: http://www.uscis.gov/portal/site/uscis/menuitem.5af9bb95919f... The other thing was the E2 Visa, however for some unknown reason, it is not available to Indians due to lack of treaty. More info here: http://en.wikipedia.org/wiki/E-2_visa As taurussai has mentioned, work on the application and interview and the amazing YC community can help sort out the rest. P.S. - If any of YC Community would be open to sharing how to make it work, it would be great for future YC candidates.