I mean yes. We've hosted internal apps that have four nines reliability for over a decade without much trouble. It depends on your scale of course, but for a small team it's pretty easy. I'd argue it is easier than it has ever been because now you have open source software that is containerized and trivial to spin up/maintain.

The downtime we do have each year is typically also on our terms, not in the middle of a work day or at a critical moment.