Loss of a loved one is a very specific event, intelligence is a very broad idea that isn't even well defined. I have no idea what this means: "concepts on orders of magnitude higher levels than hormones". I guess your intelligence is just much higher than mine.
If you have depression or another condition affecting your affect and your emotions, sure. Otherwise it's pretty obvious to anyone that concepts on orders of magnitude higher levels than hormones being correlated with happiness, or if you prefer, those concepts having a significant effect on the overall action of those hormones.