Visually I think it's rather pleasing. It's different and the horizontal scrolling might not be everyone's cup of tea, but screens seem to be getting wider so it makes sense that sites start adopting a more horizontal oriented approach to web design to accommodate larger resolution screens.
I do find it kind of ironic the design team use Mac's and people are saying that the new MySpace looks like it got inspiration from the Windows 8 Metro / People Hub, haha.
It seems very tablet like. Side scrolling isn't a big deal on a touch device. Not sure how I'd like it in a browser with a mouse that only scrolls one way, but the video looks nice at least.
It's probably an alignment issue with my brain scrabbling to differentiate content.
I'm also a fan of paging over scrolling. So it will be interesting to feel how this works. Perhaps scrolling with the finger lets you focus better than scrolling with the keyboard or pointer.
Great work!
It looks stunning I hope it works as well as it looks cause that is probably more important than the visual aesthetics.