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Re:A Gemma model helped discover a new potential cancer ther... by alganet on Wednesday October 15, 2025 @04:26PM (#45597969)
I am concerned about this kind of technology being used to circumvent traditional safeguards and international agreements that prevent the development of biological weapons.
Re:A Gemma model helped discover a new potential cancer ther... by vessenes on Wednesday October 15, 2025 @08:03PM (#45599920)
Well you might be pleased to know that there are large safety teams working at all frontier model companies worried about the same thing! You could even apply if you have related skills.
Re:A Gemma model helped discover a new potential cancer ther... by alganet on Wednesday October 15, 2025 @08:14PM (#45600017)
Are these safety teams subject to the oversight of more estabilished international agreements and safeguards?
Re:A Gemma model helped discover a new potential cancer ther... by vessenes on Wednesday October 15, 2025 @09:07PM (#45600387)
I mean.. they work within the legal frameworks of very large corporations with nation state engagement. It's not like they're autonomous anonymous DAOs
Re:A Gemma model helped discover a new potential cancer ther... by canyon289 on Wednesday October 15, 2025 @09:28PM (#45600486)
Hi! I work directly on these teams as a model builder and have talked to my colleagues are the other labs well.

All our orgs have openings and if you also could consider working for organizations such as the UK AISI team and other independent organizations that are assessing these models. It's a critical field and there is a need for motivated folks.

Re:A Gemma model helped discover a new potential cancer ther... by alganet on Wednesday October 15, 2025 @10:43PM (#45600892)
That does not answer my question.
Re:A Gemma model helped discover a new potential cancer ther... by vessenes on Friday October 17, 2025 @02:47PM (#45620437)
It does. It's just your worldview is pretty black and white. All of these teams ultimately answer to executives that report to a board, that board is guided by a Chief Legal Officer that engages with regulators among other groups. Some guidance will come back as direct control. A lot might come back as soft preferences / guidance to executives.
Re:A Gemma model helped discover a new potential cancer ther... by alganet on Friday October 17, 2025 @06:13PM (#45622757)
My worldview considers the existance of lobbies and human neglect. It seems more nuanced than "believe the management" rethoric.
Re:A Gemma model helped discover a new potential cancer ther... by JumpCrisscross on Thursday October 16, 2025 @07:01AM (#45603899)
> the oversight of more estabilished international agreements and safeguards?

“Unlike the chemical or nuclear weapons regimes, the [Biological Weapons Convention] lacks both a system to verify states' compliance with the treaty and a separate international organization to support the convention's effective implementation” [1].

[1] https://en.wikipedia.org/wiki/Biological_Weapons_Convention

Re:A Gemma model helped discover a new potential cancer ther... by alganet on Thursday October 16, 2025 @01:47PM (#45608449)
The UN has a page on Biological Weapons.

https://disarmament.unoda.org/en/our-work/weapons-mass-destr...

You can read more about the efforts for disarmament there.

Re:A Gemma model helped discover a new potential cancer ther... by JumpCrisscross on Thursday October 16, 2025 @03:22PM (#45609599)
Where is there oversight?

Biological weapons compliance is entirely voluntary. We don’t have international monitors watching America and Russia’s smallpox stockpiles. That’s left to each nation.

Re:A Gemma model helped discover a new potential cancer ther... by alganet on Thursday October 16, 2025 @03:34PM (#45609741)
Your angle is "there is no oversight, why are you asking for it?". It's the same overall angle as the guy who was spreading covid rumours here in this thread.

There are efforts at estabilishing it though. And it's hard and expensive for wet labs, but it could be much simpler for things like simulating biological pathways.

One could also see your response as "other nations are developing threats, we should race", which I personally think is misguided.

Instead of these petty armchair discussions, we should instead focus on being more serious about it.

Re:A Gemma model helped discover a new potential cancer ther... by bix6 on Wednesday October 15, 2025 @11:18PM (#45601105)
I thought openAI gave up on safety when Anthropic splintered off as well as when they engaged ScaleAI to traumatize people for RLHF?

Or Google when they fired Timnit?

Re:A Gemma model helped discover a new potential cancer ther... by nl on Thursday October 16, 2025 @01:39AM (#45601793)
The GPT5 system card is 59 pages. Pages 5 to 56 address safety in various forms.

https://cdn.openai.com/gpt-5-system-card.pdf

Re:A Gemma model helped discover a new potential cancer ther... by jackblemming on Wednesday October 15, 2025 @10:06PM (#45600711)
Seems like no matter how positive the headline about the technology is, there is invariably someone in the comments pointing out a worst case hypothetical. Is there a name for this phenomenon?
Re:A Gemma model helped discover a new potential cancer ther... by peddling-brink on Wednesday October 15, 2025 @10:14PM (#45600746)
Rational discourse? Not working for a marketing team? Realism?
Re:A Gemma model helped discover a new potential cancer ther... by OJFord on Wednesday October 15, 2025 @11:34PM (#45601179)
Pessimism?
Re:A Gemma model helped discover a new potential cancer ther... by collingreen on Wednesday October 15, 2025 @10:15PM (#45600749)
Not believing everything you read on the internet? Being jaded from constant fluff and lies? Not having gell-mann amnesia?

I get your sentiment of "why you gotta bring down this good thing" but the answer to your actual question is battle scars from the constant barrage of hostile lies and whitewashing we are subject to. It's kind of absurd (and mildly irresponsible) to think "THIS time will be the time things only go well and nobody uses the new thing for something I don't want".

Re:A Gemma model helped discover a new potential cancer ther... by jsnell on Thursday October 16, 2025 @04:42AM (#45602924)
Performative cynicism?
Re:A Gemma model helped discover a new potential cancer ther... by trhway on Thursday October 16, 2025 @12:25AM (#45601454)
We’ve just had a virus - specifically engineered to be highly infectious for humans - escaping the lab (which was running very lax safety level - BSL2 instead of required BSL4) and killing millions and shutting down half the globe. So I’m wondering what safeguards and prevention you’re talking about :)
Re:A Gemma model helped discover a new potential cancer ther... by LeoPanthera on Thursday October 16, 2025 @12:31AM (#45601475)
Don't spread misinformation. This myth is widely believed only by Americans.

https://en.wikipedia.org/wiki/COVID-19_misinformation#Virus_...

Re:A Gemma model helped discover a new potential cancer ther... by 4793273022729 on Thursday October 16, 2025 @03:10AM (#45602273)
He says and quotes Wikipedia.
Re:A Gemma model helped discover a new potential cancer ther... by trhway on Thursday October 16, 2025 @12:41AM (#45601522)
This myth is documented in the EcoHealth Alliance publicly available NIH and DARPA grants documents among others. Wrt your link - Wikipedia unfortunately isn’t subject to the law like those grants.
Re:A Gemma model helped discover a new potential cancer ther... by alganet on Thursday October 16, 2025 @12:57AM (#45601588)
Covid is irrelevant to the discussion I opened. You're trying to steer the discussion into a place that will lead us nowhere because there's too many artificial polemics around it.

The only thing to be said about it that resonates with what I'm concerned with is that anyone that is good in the head wants better international oversight on potential bioweapons development.

Re:A Gemma model helped discover a new potential cancer ther... by alganet on Thursday October 16, 2025 @12:54AM (#45601582)
You're trying to deflect the discussion into a polemic tarpit. That's not going to work.

I do not endorse the view that covid was engineered. Also, I consider it to be unrelated to what I am concerned about, and I will kindly explain it to you:

Traditional labs work with the wet stuff. And there are a lot of safeguards (the levels you mentioned didn't came out of thin air). Of course I am in favor of enforcing the existing safeguards to the most ethical levels possible.

However, when I say that I am concerned about AI being used to circumvent international agreements, I am talking about loopholes that could allow progress in the development of bioweapons without the use of wet labs. For example, by carefully weaving around international rules and doing the development using simulations, which can bypass outdated assumptions that didn't foresaw that this could be possible when they were conceived.

This is not new. For example, many people were concerned about research on fusion energy related to compressing fuel pellets, which could be seen as a way of weaving around international treatises on the development of precursor components to more powerful nuclear weapons (better triggers, smaller warheads, all kinds of nasty things).

Re:A Gemma model helped discover a new potential cancer ther... by trhway on Thursday October 16, 2025 @01:41AM (#45601807)
>For example, by carefully weaving around international rules and doing the development using simulations, which can bypass outdated assumptions that didn't foresaw that this could be possible when they were conceived.

Covid development in Wuhan was exactly a careful weaving - by means of laundering through EcoHealth - around the official rule of "no such dangerous GoF research on US soil". Whether such things weaved away offshore or into virtual space is just minor detail of implementation.

Re:A Gemma model helped discover a new potential cancer ther... by alganet on Thursday October 16, 2025 @01:53AM (#45601870)
Still irrelevant to what I brought up.