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Re:The NIH ordered me to stop my 'dangerous' gain-of-functio... by estearum on Tuesday October 07, 2025 @12:24PM (#45505184)
Instead of continuing to muddy the conversation why don’t you just settle it by providing a clear answer to this question?:

What should we do differently depending on the outcome?

The miasma alternative for cholera is another excellent illustration of my point, not yours. The answer to whether miasma theory or contaminated wells was correct very obviously had bearing on how you’d mitigate the problem, and this characteristic was totally evident even before answering the question.

If someone could specifically state what we should do differently depending on the answer, I’m amenable to it. But you haven’t done that because the answer is: nothing!

Re:The NIH ordered me to stop my 'dangerous' gain-of-functio... by timschmidt on Tuesday October 07, 2025 @12:30PM (#45505279)
Other folks here have tried to have that conversation with you: https://news.ycombinator.com/item?id=45502746

Feel free to respond to them.

Re:The NIH ordered me to stop my 'dangerous' gain-of-functio... by estearum on Tuesday October 07, 2025 @12:38PM (#45505391)
No actually if you read two comments further, you’ll notice they said “indeed” it doesn’t make a difference.

Then tried a poorly reasoned analogy to reach their prior conclusion indirectly.

I note that, once again, you can’t answer the simple question that’d settle the debate in your favor.

Re:The NIH ordered me to stop my 'dangerous' gain-of-functio... by timschmidt on Tuesday October 07, 2025 @01:03PM (#45505711)
We understand their responses very differently then. I trust that others will make their own decisions having read the thread.