Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by timschmidt on Tuesday October 07, 2025 @09:25AM
(#45502780)
> We should do this regardless of whether this pandemic came from a lab.
Sadly, the funding to do so will not be made available without reason. Reason which could come from determining the root cause.
Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by estearum on Tuesday October 07, 2025 @09:28AM
(#45502816)
Which literally won't happen because the information does not exist in the world. Unless you're expecting a Chinese researcher to identify themselves as patient 0.
So your fixation on root causing is having precisely the effect that I mention, which is preventing mitigation.
Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by timschmidt on Tuesday October 07, 2025 @09:34AM
(#45502874)
> So your fixation
Friend, I don't seem to be the one with a fixation here. Please avoid personal attacks.
Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by estearum on Tuesday October 07, 2025 @09:36AM
(#45502908)
Your declared imperative? Your stated goal? Your admitted priority?
It's not a personal attack, it is referring to a belief that you stated you have.
Not sure what's triggering about "fixation" but feel free to swap out any of the above phrases.
Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by timschmidt on Tuesday October 07, 2025 @09:39AM
(#45502953)
> declared imperative? Your stated goal? Your admitted priority?
No, I'm not sure any of those phrases fit a casual conversation on a message board.
> Not sure what's triggering
Are you triggered? I'm not triggered. I just posted a link, and responded when prompted.
Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by estearum on Tuesday October 07, 2025 @09:43AM
(#45502992)
Huh, if you don't believe it's important to discover the origin of COVID then I'm not sure what we've been talking about. Have a good day!
Re:The NIH ordered me to stop my 'dangerous' gain-of-functio...
by timschmidt on Tuesday October 07, 2025 @10:22AM
(#45503420)
I'm not sure what you've been talking about either! Seems like you have beef with someone about epidemiology. I don't know who. Or maybe you're just burnt out on discussion of the topic, which happens. Others of us are not. And that is OK.
I actually think the obsession with root cause makes it less likely we'll create the interventions we need. First because it suggests to people that the root cause of this pandemic changes the risk calculation for future pandemics (it doesn't) and secondly because the mitigations of one root cause are distinct from the mitigations for another. And we actually need to mitigate both zoonotic and lab leak threat vectors.
> Your scenario of ending all GoF research might be on the table
To be clear I did not suggest this. GoF is an extremely broad term which includes e.g. mutating E. coli to produce insulin or other biologics. Increasing contagiousness of a lethal agent or increasing lethality of a contagious agent should become much more of a no-go zone though. That's a small subset of GoF research.
> locating GoF research labs away from densely populated metropolitan areas and international airports.
We should do this regardless of whether this pandemic came from a lab.