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Re:Genomic analyses of hair from Ludwig van Beethoven (2023) by divbzero on Tuesday September 30, 2025 @04:39PM (#45430934)
Well, they managed to analyze DNA from centuries-old hair in this paper.

From the methods section:

> Nuclear DNA in hair has an extremely low average fragment length owing to the activity of endonucleases expressed during hair formation.

But the researchers made adjustments for that during sample prep before sequencing, and alignment after sequencing.

Re:Genomic analyses of hair from Ludwig van Beethoven (2023) by gausswho on Tuesday September 30, 2025 @09:40PM (#45433430)
Musical gholas inbound.