In this case, Genetic Programming uses trees as its representation, and so it could be used as a tree-based classifier, but the OP has already indicated that he expects enormous numbers of rules, necessitating huge trees. For Genetic Programming, this translates into a gigantic search space.
As it was my thesis work, I'm always ready to promote Genetic Programming where appropriate. This is not the place. There are better tools for this task.
But that aside I believe that such a search space could be handled by GP. That very problem is what I've been tackling for sometime now. Its position on my list reflects that particular bias. But there are techniques. I use EDA's like MOSES and was heavily inspired by http://www-ia.hiof.no/~rolando/ but have my own original contributions. The method is also interactive for tough problems, these really help in reducing the search space. Although I have not succeeded in a use yet, I have been thinking hard about how category theory could be used to constrain space or perform particular automatic transofrmations (https://www.cs.ox.ac.uk/jeremy.gibbons/publications/origami...., https://www.cs.ox.ac.uk/people/jeremy.gibbons/publications/a...).
For example, understanding the spectral theorem makes SVD (hence PCA) and the DFT class of algorithms much clearer. Understand the notion of Lp-Norms, convexity, adjoints, loss functions and regularization and a whole bunch of seemingly different algorithms collapse into facets of the same thing. Hook it up to automatic differentiation then some optimization algorithms and you can write anything from Neural networks, SVMs, regularized logistic regression to Non negative tensor factorization in a few lines. You stop making arbitrary divisions between classification or optimization. Much the same kind of collapse can be done for the dual [2] notion of probabilistic algorithms by thinking in terms of graphs, simplices, parametrizations, families and conjugacy.
The best thing from all this is you stop thinking of which algorithm should I use and start thinking of what do I want to do? What is the best mathematical model for this? What would really be great would be a machine learning language. Where one could work with things akin to folds and maps on various structures and manifolds and disappear the incidental complexity. Stuff like [3] is really encouraging for that direction.
[1] The problem of learning a distribution usually is called unsupervised learning, but in this case, supervised learning formally is a special case of unsupervised learning; if we admit that all the functional relations or associations that we are trying to learn have any element of noise or stochasticity, then this connection between supervised and unsupervised problems is quite general.
http://www.princeton.edu/~wbialek/our_papers/bnt_01a.pdf
[2] http://golem.ph.utexas.edu/category/2007/01/duality_between_...
[3] http://www.ipam.ucla.edu/publications/gss2012/gss2012_10605....