I just run Debian Trixie with almost no problems. I build the kernels I use off the upstream release cycle (so, 6.17-rc6 right now). I build with LLVM Full LTO, not because it's necessarily faster, but because I want to find bugs in it :)

For some reason the video acceleration in Steam itself will break running games if you alt-tab back and forth. But it can be disabled in the menus, and I haven't missed it at all.