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A comment on Removing newlines in FASTA file increases ZSTD compression ratio by 10x. Parent comment

Re:Removing newlines in FASTA file increases ZSTD compressio... by Gethsemane on Monday September 15, 2025 @10:49AM (#45250377)
Unfortunately, when you write a program that doesn't wrap output FASTAs, you have a bunch of people telling you off because SOME programs (cough bioperl cough) have hard limits on line length :)
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Re:Removing newlines in FASTA file increases ZSTD compressio... by o11c on Monday September 15, 2025 @03:27PM (#45253904)
You can use content-defined chunking to wrap at a predictable place so that compression still works.
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Re:Removing newlines in FASTA file increases ZSTD compressio... by sharedptr on Tuesday September 16, 2025 @02:28AM (#45258721)
Is BioPerl still standard, did people move to BioPython?

When I was shown BioPerl I was tempted to write a better, C++ version, but was overwhelmed by other university stuff and let it go.

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