A good place to read more about these: https://examine.com/supplements/n-acetylcysteine/?show_condi...

Truth be told, none of either prescription or OTC stuff has any solid research backing it. Some people, especially on HN are obsessed with living long and are always prompt to try the weirdest experimental stuff. Reasonable people should remember what the COVID period was on this website, and act accordingly...

If you want to live long, be bipolar and take lithium.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7553080

(no don't, it's hell on earth)

Melatonin is just for jetlag/otherwise shifted sleeping schedule, are people using it as an anti aging drug?

Melatonin is always made from serotonin.

Serotonin is made from tryptophan, which can also be made into niacin.

Taking tryptophan and niacin as a supplement will boost both serotonin and melatonin naturally, assuming these pathways are working properly.

However, this can be dangerous in the presence of an SSRI.