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Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by naravara on Tuesday August 05, 2025 @03:09PM (#44802775)
The weight loss mechanism largely just comes from suppressing appetite though, so it still lines up with the penance for sin narrative. It’s not that different from wearing a hair-shirt and whipping yourself if you find yourself having lustful thoughts. Only instead of a whip you just feel kind of uncomfortable and nauseous if you eat too much.
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by radiofreeeuropa on Tuesday August 05, 2025 @03:31PM (#44803104)
I'd describe the effects as basically the opposite of self-torture. Self-torture is dieting/fasting without the drugs. With them, it's great. No afternoon light-headedness and difficulty concentrating, no hunger pangs, no "hangry" effect, no cravings you have to keep suppressing. Just smooth sailing. (though experiences do seem to vary—as do dosage levels)
Re:Ozempic Shows Anti-Aging Effects in Trial, Reversing Biol... by cheald on Tuesday August 05, 2025 @03:31PM (#44803102)
That's true of semaglutide, but newer peptides like tirzepatide (a dual-agonist) and retatrutide (a triple agonist) have additional effects like improving insulin sensitivity, and simultaneously slowing the release of glucagon and activating glucagon receptors, which directly increases fat oxidation and thermogenesis.