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Re:Psilocybin produces substantial sustained decreases in de... by adamgordonbell on Friday July 18, 2025 @08:17AM (#44603870)
2 to 5 grams dried psilocybe cubensis, per chatgpt.
Re:Psilocybin produces substantial sustained decreases in de... by TrackerFF on Friday July 18, 2025 @08:29AM (#44603958)
You’ll be tripping balls on that amount. 5g is close to a heroic dose.

EDIT: Never mind, didn't see that it was cubensis - which might take more due to being weaker than regular wild semilanceata.

Re:Psilocybin produces substantial sustained decreases in de... by throwaway330935 on Friday July 18, 2025 @10:27AM (#44604996)
I've been doing some recent research and testing, and here's what I have found: I'm talking about the "Penis Envy" strain, which is quoted as being ~30% more potent than typical. 2g is the edge of where I start getting visual artifacting, and only sometimes. 3g, which I have not tried, was quoted as being towards the upper end of a "theraputic dose", and 6g as the upper end of a recreational dose. Some friends with much more experience consider 1g to be microdosing, FWIW. 0.25g I can't feel at all. .5g I start to feel some euphoria and 1g to 1.5g I start to feel "high" but with no noticeable psychedelics or just minor visual artifacting when I'm reading.

I don't really have anxiety or depression. I do have a fairly high stress family life, wife and kiddos have lots of issues. A few weeks ago I had 2g on an empty stomach on a Sunday and I just listened to music for ~4 hours and it was like I had a vacation. I hadn't enjoyed listening to music so much for 20-30 years. Also, I seem to feel kind of sleepy when I'm trippy, but afterwards I'm wide awake for 4-5 hours. So evening dosing is best avoided.

It's kind of great, for me personally, living in a state where it has been decriminalized.

Re:Psilocybin produces substantial sustained decreases in de... by amanaplanacanal on Friday July 18, 2025 @12:18PM (#44606498)
Personal response may vary. At .15 grams of dried mushrooms I can definitely feel effects, while still be able to perform normal life functions.
Re:Psilocybin produces substantial sustained decreases in de... by locallost on Friday July 18, 2025 @08:37AM (#44604031)
I don't know if that's true or false, but I would certainly not trust chatgpt blindly in this case.
Re:Psilocybin produces substantial sustained decreases in de... by mock-possum on Friday July 18, 2025 @08:33AM (#44603990)
And I’d consider about an eighth to be a dose, so that sounds like it’s in the right neighborhood.
Re:Psilocybin produces substantial sustained decreases in de... by throwaway330935 on Friday July 18, 2025 @10:13AM (#44604864)
I learned from an episode of "The Studio" that by "an eighth" you are likely referring to an eighth of an ounce is around 3.5 grams. Dude thought he got really mild shroom laced chocolates ("an eighth of a gram") and much hilarity ensued.
Re:Psilocybin produces substantial sustained decreases in de... by scellus on Friday July 18, 2025 @08:36AM (#44604026)
Here's a rough breakdown from Claude:

"[...] psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect [...]

Psilocybe cubensis (most common): Contains about 0.5-1.0% psilocybin by dry weight. Since psilocybin converts to psilocin in the body at roughly a 1:1 ratio by active effect, 30mg of psilocin would be equivalent to roughly 3-6 grams of dried P. cubensis.

Psilocybe semilanceata (liberty caps): Much more potent at 1-2% psilocybin content, so you'd need only about 1.5-3 grams dried.

Psilocybe azurescens: Even more potent at 1.5-2.5% psilocybin, requiring roughly 1-2 grams dried.

Important caveats:

- Individual mushrooms within the same species can vary by 3-5x in potency Growing conditions, harvesting time, and drying/storage methods all affect potency

- The caps are typically more potent than stems

- Fresh vs. dried makes a huge difference (fresh mushrooms are ~90% water)"

Have to note that the paper is from 2016; for those really interested, it's good to read recent review papers.

Re:Psilocybin produces substantial sustained decreases in de... by skeezyboy on Friday July 18, 2025 @11:44AM (#44606027)
there was a study recently showing no difference in caps v stems
Re:Psilocybin produces substantial sustained decreases in de... by sampl3username on Friday July 18, 2025 @08:55AM (#44604183)
@grok is this true????
Re:Psilocybin produces substantial sustained decreases in de... by scellus on Friday July 18, 2025 @09:02AM (#44604222)
lol