You can get these drugs with a vial and needles and it’s cheaper that way. Not familiar with the autoinjectors, but the instructions when using a vial and insulin needles is definitely to pull back.
Peptides don’t have the same negatives as say insulin, but preferable to not have them in your bloodstream nonetheless.
Either way super simple and quick. Fairly painless. I had a weird rash one time, but apart from that a total of about 15 injections haven't had any issues on either Ozempic or Trulicity in terms of injections. Others may have difficulties, but it's been super easy IMO.