n=1 isn't necessarily data, and I have other questions (the formate concentration of the probiotic variant is 4x over JH1140, but JH1140 is itself a mutant; what's the formate production of an average wildtype strain?). Methanol can cause blindness in as little as 4mL, so the amounts we're talking about are relatively small; 4mL of methanol ≅ 99mmol.