i paid 600 for a rental this summer. it was a van, and it was pickup and dropoff in different locations, but there are certainly scenarios in which you need to spend hundreds of dollars on a rental car. Yes you can do it for cheaper, but that depends on location, time, special needs, etc.

Ah ok. I was looking at your original problem, which was travelling 450 miles to visit your family. That problem, at least to me, didn't involve cargo vans and one-way dropoffs. Sorry.