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Re:Hackable AlphaFold 3 without Docker or MSAs by chaitjo on Friday June 13, 2025 @03:59PM (#44271731)
his is a lightweight, hackable way to run AlphaFold 3 that lets you experiment without the massive MSA databases or Docker overhead. Perfect for tinkering on your laptop or single GPU server - just install, drop in your sequences, and start predicting. No 100GB downloads, no container bloat, just pure structure prediction you can play with in a Jupyter notebook.