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Re:Administering immunotherapy in the morning seems to matte... by jcims on Monday June 09, 2025 @09:23AM (#44224257)
Well the concept is now being studied quite closely. Had someone taken it seriously thirty years ago it's quite possible that the net amount of suffering that millions of patients have endured since then could have been reduced.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9599830/

I'm comfortable calling that shameful. Not on any one in particular, it's a systemic problem that could be reduced with sufficient tenacity and courage to take risks.

Re:Administering immunotherapy in the morning seems to matte... by ch4s3 on Monday June 09, 2025 @11:33AM (#44225537)
There's limited time and a finite supply of doctors and researchers. They can't study everything that's promising all at once, and good ideas fall through the cracks all of the time.
Re:Administering immunotherapy in the morning seems to matte... by JamesSwift on Monday June 09, 2025 @12:25PM (#44226112)
I think this clears a bar of things that are useful and simple to study. Theres basically no effort involved. If it ends up beneficial we just update job postings from 'daytime infusion tech' to 'nighttime infusion tech'. Instant improvement in outcomes. I doubt you even need to clear this in any way to get the study greenlit.
Re:Administering immunotherapy in the morning seems to matte... by jcims on Wednesday June 11, 2025 @10:22AM (#44247940)
Agreed. Scheduling is patient discretion anyway. It's the lowest bar possible as far as I can tell.
Re:Administering immunotherapy in the morning seems to matte... by refurb on Monday June 09, 2025 @01:14PM (#44226659)
> Had someone taken it seriously thirty years ago it's quite possible that the net amount of suffering that millions of patients have endured since then could have been reduced.

You can only say that with hindsight because of the data over the past 30 years.

What if the data showed the opposite? Then the doctor would have given his patients a worse outcome all on a "hunch".