For your example, probably. Different people will have different compulsive behaviors. I painted my kitchen cabinets shortly after moving in... I didn't do the best job of it, and I do notice the blemishes, inconsistencies and bleed through as well as a few spots that chipped over the last 6 years or so. Not enough that I stress over it, or even really think about it in general, but recognize.
I don't think I'd ever want something all that monochrome for myself. To me, subdued isn't about monochrome so much as limiting the noise. I don't even mind a sharp contrast, such as a colorful photo/painting. It's what I can only describe as visual noise that gets me. Especially with patterns that aren't really something you'd see in nature.
I saw some pictures from a house where everything was white. The walls were white, the tables and chairs were white, the pillows were white, lamps were white, etc. But I bet the owner didn't see it as everything being white, like I did. I bet that when they'd look at the same pictures, they'd see all the little details here and there that were not white, or not quite white enough. I imagine them being in a constant state of stress over the non-white blemishes.
I don't know them, I just saw the pictures, so I don't truly know how they feel, I could be just imagining things. But my gut feeling is that someone with a home like that is not at ease with themselves.