I have been running lockdown mode for a while now and it can be painful for shopping but usable. You can disable it on a per site basis in Safari. Stolen device protection mode on also.

To do it and enable side loading you need to do two resets to enable developer mode. I am able to enable a configuration profile also without a problem. It was installed and enabled pre-lockdown and re-enabled in lockdown mode. I just enabled location services for camera and it correctly gps tagged my photo.

The only pain points I have are if someone texts me something other than a picture which is a lockdown feature. For some reason usps tracking webpage fails on all browsers except on Firefox/Firefox focus browser. A few heavily tracked apps or shopping websites don’t like it but tolerate it. Pain: You cannot search your iMessages. I can turn lockdown off on a per app basis excluding iMessage also but have not needed to.