I don't think this will change anything big. A leader is important to a company, but a leader needs to be able to create the kind of culture that runs itself when they're away. I'm guessing that Jobs did a good job of instilling the culture that Apple has today in a way that will continue because of how the workers see themselves and the company. It's sad to see him undergoing such medical problems and I wish him a speedy recovery, but I think Apple will do fine without him because he's given them purpose and direction and a definition that lasts beyond him.

I'm sure we all wish you a speedy recovery and many years of health!