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A comment on The serotonin theory of depression: a systematic review of the evidence (2022). Parent comment

Re:The serotonin theory of depression: a systematic review o... by IX-103 on Friday February 28, 2025 @05:32PM (#43212581)
Yeah, the new "weight-loss" drugs seem to have significant psycho-active effects on the dopamine reward pathway. That seems like it may provide a more direct treatment than SSRIs.
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Re:The serotonin theory of depression: a systematic review o... by arcticbull on Friday February 28, 2025 @07:31PM (#43214010)
Yeah calling them weight-loss drugs seems to really be under-selling them. I suspect the anti-depressant action has more to do with BDNF-TrkB and IL-6 signaling though!
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