Same sort of situation here. Used to study aerospace engineering in college, then transferred to a new school to study music technology. Met a great co-founder and we'd been working on a startup specifically centered around the arts, but it fell apart as the school year came to an end.

Now that summer has started, we've begun work on a different startup (a new type of search engine, sort of...), but it's kind of new territory. We're pretty confident we're aiming at a fairly large target audience, but still scared as this is completely outside our area of expertise.