That being said, new treatments are being discovered all the time. I suffered from a TBI and I am part of a study. The medication I am on is 4 decades old, but it helps folks with TBIs, long COVID, ME/CFS, etc. with an 85% success rate. It is helping me as well. My working and long term memory have improved along some other stuff as well.

That being said, I feel bad for people with chronic pain. A sibling had chronic pain for decades, got accused of being lazy, etc. After seeing dozens of doctors spanning those decades, they finally found the cause and surgery fixed it. For every success like that, there are hundreds more that never see relief.