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Re:Migraine is more than a headache – a rethink offers hope ... by groos on Tuesday February 18, 2025 @06:18PM (#43096393)
I started having migraines at 8 years of age, several a week. This persisted all through my life till 42 years later, I had a blood pressure emergency where I ended up in ER with 190/100 blood pressure. Thankfully, it never repeated and was never diagnosed but as a consequence I was put on Olmesartan, a blood pressure medication that relaxes the blood vessels. Eventually, the dose was reduced to the lowest, 5mg, once a day, to which I added 240mg magnesium glycinate, which they sell in Costco. I have been mostly migraine free since for several years and ones I do get are mild compared to before.

My cardiologist, who prescribed the blood pressure medication, is mystified saying that while beta blockers are a migraine prevention medication, olmesartan isn't a beta blocker and maybe it was just my (mild) hypertension which needed to be treated. I doubt that I had hypertension when I was 8 but I'm just thankful that decades of pain have come to an end.

Re:Migraine is more than a headache – a rethink offers hope ... by fireflash38 on Tuesday February 18, 2025 @08:29PM (#43097484)
Hmm, I was prescribed Verapamil (calcium channel blocker, also a blood pressure medication), and they helped reduce the severity of my migraines with aura for a while. I eventually went off it, and haven't had near as many since. Early twenties was so awful for those migraines.
Re:Migraine is more than a headache – a rethink offers hope ... by nooron on Tuesday February 18, 2025 @08:33PM (#43097509)
Did you find Verapamil had any mood altering or cognitive properties for you? I take it for migraines. I think it makes me a little more emotionally stable but a tiny bit slower cognitively, especially in the mornings. It's a good trade off, especially in light of how it basically stopped my migraines, but it's one I have perceived.
Re:Migraine is more than a headache – a rethink offers hope ... by nik9000 on Tuesday February 18, 2025 @09:02PM (#43097686)
I'm on a sartan and my migraine doctor thought it might help.
Re:Migraine is more than a headache – a rethink offers hope ... by internet_points on Wednesday February 19, 2025 @05:02AM (#43100471)
Candesartan has been massively helpful and has very mild side effects compared to beta blockers like metoprolol.