Alzheimer's biomarkers now visible up to a decade ahead of symptoms

Re:Alzheimer's biomarkers now visible up to a decade ahead o... by caycep on Saturday February 15, 2025 @02:23PM (#43061398)

Presumably, a newer generation of anti-amyloid or anti tau agents. There are current gen ones (targeted monoclonal ab ) which aren’t that incredibly effective but there’s some thought that maybe that’s due to treating the wrong patients at the wrong time, vs starting therapy earlier on

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Re:Alzheimer's biomarkers now visible up to a decade ahead o... by WillyWonkaJr on Saturday February 15, 2025 @02:34PM (#43061500)

Didn't it turn out that the amyloid plaque hypothesis was based on a fraudulent paper?

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Re:Alzheimer's biomarkers now visible up to a decade ahead o... by pedalpete on Saturday February 15, 2025 @06:29PM (#43063541)

Not exactly. There are "issues" with one of the early papers, and I believe some other follow-up papers, but not all research had these issues.

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