Not really. Uv is great but it doesn't really help here. If an app uses Python as its configuration file format then the app is running Python. It's going to do `python3 config.py` or similar. It doesn't know anything about uv.

So you would still need to create a uv project, run `uv sync` and `uv activate` or whatever and then run your app. Not practical.

The only option if you use Python as a config file format is to stick to old features (Python 3.6) and not use any third party libraries. But op was saying third party libraries are one of the benefits of using Python...