Is this a normal soda consumption levels in humans or when feeding it to rats at some obscene rate?
I'm not saying it is good for you, but we need facts not blind statements with no context.
> We identify NAS-altered microbial metabolic pathways that are linked to host susceptibility to metabolic disease, and demonstrate similar NAS-induced dysbiosis and glucose intolerance in healthy human subjects. Collectively, our results link NAS consumption, dysbiosis and metabolic abnormalities, thereby calling for a reassessment of massive NAS usage
I’d be glad to see the full paper
https://pubmed.ncbi.nlm.nih.gov/25231862/
> normal soda consumption levels in humans
I note that "normal" here should be read as "common during the last 50years (or less)", where the last 50ears is quite reductive in human dietary habits.
https://www.researchgate.net/publication/265791239_Artificia...
I would be very reluctant to read too deep into this given saccharin is known to behave very differently in animal models - for a long time it was thought to cause bladder cancer, but follow up studies proved that it’s an idiosyncratic reaction only found in female lab rats and no other gender/species combination. Not to mention the dose used was unrealistic to begin with.
It’s entirely plausible that sugar analogs like sucralose and non-calorific sugar alcohols such as erythritol and maltitol can cause long term changes in the gut biome but high quality evidence is still lacking.
For me I was absolutely shocked at how a soda being sugar free didn't have to imply it was like drinking horse piss. I had tried Diet Coke a few times and assumed that was what you had to deal with if you went sugar free. One day someone gave me a Coke Zero and it was actually not bad, even if not quite being as good as Coke. This led me to try some others like Dr Pepper Zero Sugar for which I thought "what the hell, this tastes better than Dr Pepper???".
Obviously which are better will vary by person and most people will, overall, like sodas with actual sugar more often but if everyone tried a few different options they might be surprised how little they'd have to trade down on the soda for, if anything, to drastically drop their sugar intake.