It's getting very philosophical, without a (perhaps impossibly complex/fraught) model of real-world programmers using all available languages doing just what you ask there is no way to find the sweet-spot. I've given some rules of thumb why python still rules and why things in general favor standard forms easily reviewable by humans and peppered with magic only understandable by geeks.

edit: you've removed a line while I was resonding like: "maybe go is a sweet-spot"

I think if you are looking to replace python as a runtime you'd maybe be better off arguing for safety, python is much more easily corruptible so if maybe you don't trust your machine(s) you are training on and don't want to be mislead by someone hacking your initializations then arguably running a compiled program with certain guarantees is safer.