However, while the site creator does have to meet the disabled halfway, the disabled person is responsible for having whatever type of equipment they need to make it work - ie screenreaders
Just do your job right. Not saying you should test some unique Firefox config but at least the default version is to be tested.
Hell, I've seen people here indicating that they just tell desktop Mac users to "install Chrome". Such carelessness is bad for business. Web development sure could raise its bar.
For the longest, Amazon Connect’s - AWS hosted call center software - call flow builder only worked with Chrome.
Even for B2C users, using Chrome is not a deal breaker. If they are okay with using shitty Electron apps, they will be okay with using Chrome for Mac.
And before you say "that's their choice," you're the one who is breaking the functionality. Nothing about using a VPN or linux or Firefox creates any problem for TCP/IP or https.