Well yes and no. Strain on the skeleton from excess muscle isn't particularly a problem unless someone is really huge or does a lot of running. The skeleton adapts to handle the load. Having more strength in the muscles that stabilize joints actually reduces the risk of joint injuries — up to a point.

https://peterattiamd.com/belindabeck/

The medical problems with excess muscle mass tend to be more on the cardiovascular system than the skeleton. And the process of gaining a lot of muscle mass can increase the risk of musculoskeletal injuries (especially if using PEDS), which is a key confounding factor when looking at population health statistics.