To the contrary, I am extremely encouraged by his complaints. Because his problems basically boil down to Hard Engineering problems - nothing he said was a lack that required basic science (hard). If you will recall it was only 10 years ago that it cost millions and ~10 years to sequence one human genome.

And the problems he is listing, all it takes is something like memristors to catch on to lay waste to his worries on data and computational limits and replace them with "I remember back in the day when petabytes were considered a firehose".