HPV vaccination: How the world can eliminate cervical cancer

Re:HPV vaccination: How the world can eliminate cervical cancer by lumb63 on Saturday November 09, 2024 @08:25PM (#42097984)

How are the authors able to discern between vaccine related events, and non-vaccine related events? There is no oracle one can consult to determine this. That’s the entire point of having a second group which was not treated - to have a reference that one can compare against to determine if outcomes were correlated with the treatment. Even then, one cannot say with certainty if the events were caused by the treatment, or simply correlated; to say that all 231 distinct serious outcomes were not caused by the vaccine seems a very extreme statement to make, and can almost be disregarded prima facie; if the researchers were infallibly able to determine what adverse events were caused by the treatment, then why would they need another group to compare to?

Similarly, while there may be ethical concerns with using a placebo, statistics and biology do not care about ethical concerns. There are real results which come from medical treatments, and ignoring them does not make them go away; it just makes us ignorant of them.

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by mplewis on Saturday November 09, 2024 @08:45PM (#42098050)

You can just read the text, you know. It's fully and freely available online.

> None of the deaths were considered by the study investigators to be vaccine-related. The five deaths in the 9vHPV vaccine group were the result of suicide (15 days after vaccination dose 1), acute lymphocytic leukemia (diagnosed 27 days after vaccination dose 3), traffic accident (226 days after vaccination dose 3), hypovolemic shock and septic shock (531 days after vaccination dose 3), and sudden death (678 days after vaccination dose 3). The five deaths in the qHPV vaccine group were the result of accidental death (airplane accident 7 days after vaccination dose 3), spinal cord injury (141 days after vaccination dose 3), gastric adenocarcinoma (diagnosed 403 days after vaccination dose 3), cervical spinal cord injury (811 days after vaccination dose 3), and cerebral hemorrhage (1114 days after vaccination dose 3).

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by mtlynch on Saturday November 09, 2024 @08:56PM (#42098093)

Sudden death and cerebral hemorrhage seem hard to declare as unrelated to the medication they took.

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by SamoyedFurFluff on Saturday November 09, 2024 @09:22PM (#42098213)

Cerebral hemorrhage over 3 years after a vaccination could actually have another cause not listed here, eg. high blood pressure or poor diet.

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by cogman10 on Saturday November 09, 2024 @09:34PM (#42098269)

Or getting hit in the head or falling down.

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by grouchypumpkin on Saturday November 09, 2024 @09:06PM (#42098141)

Sudden death almost two years later, and Cerebral hemorrhage almost three years after vaccination does seem unrelated to the “medicine they took”.

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by patmorgan23 on Saturday November 09, 2024 @09:06PM (#42098138)

Maybe but if they were related to the vaccine we would expect them to occur more than once in the study group, right?

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by mattkrause on Saturday November 09, 2024 @11:37PM (#42098567)

Yup! That’s exactly why they initially list every bad outcome before trying to rule it in/out.

For example, you might be tempted to dismiss deaths due to traffic accidents as being obviously unrelated to a drug. However, if there were a lot of them, it would be prudent to check for potential effects on reaction times or judgement.

[ Parent | on HN ]

Re:HPV vaccination: How the world can eliminate cervical cancer by MisterBastahrd on Saturday November 09, 2024 @11:12PM (#42098520)

My grandmother died of a cerebral hemorrhage. It wasn't because of the cholesterol medication she took. It was because she was on blood thinners, was old, and tripped and hit her head on the dresser while preparing for church.

[ Parent | on HN ]