Sure we don't have proof that all life will form from essentially "binary" data, (although technically ours is made of 4 bases, not 2), but it's almost axiomatic that life will find the simplest possible way to store information before it finds the more complex ways. Ergo DNA is almost binary, but quarternary instead. It's nearly digital.

Insofar as your H20 vs DNA comparison, I merely used water as a way to show relative "scale". That is, HOW MUCH fluid volume (relative to the order of magnitude of size of atoms) would it take to contain the requisite number of RNA. Because when it comes to probabilities of finding astronomically unlikely combinations, astronomically large numbers is key. I think in a mole of random Rubicks cubes, hundreds will be "accidentally solved" (I forgot those numbers, so check my math, on that one)

The reason I threw in the "give or take 2 orders of magnitude" caveat was precisely because I knew someone like you would accuse me of relating H20 to RNA in a way in which I didn't. Other planets will have different atoms, not necessary water-based life, but planets even the size of a swimming pool have the "numbers game" power to create life.

Are you aware that at high concentrations, DNA, RNA, and proteins all have serious problems? For example, DNA and RNA are highly charged, with strong repulsion effects, while also having large greasy areas. At the concentrations you're describing, the DNA and RNA would not be functional as we know it.

Right. The "thought experiment" math is a tight packing of theoretical RNA molecules, and not intended to be taken literally, without a dilution factor; but only to show [some] people their intuition is WAY off about the power of large numbers to "create" unlikely patterns.

For example, if you ask most people how many randomly occurring Rubiks Cubes will just be accidentally solved even with Avogrdro's number of them, their answer is usually zero; and unsurprisingly they're the same ones claiming there had to be a God to create even the initial replicator.