Honestly I don't think there's any quick answer, and providing specific advice on Hacker News would be playing into exactly the problem I was pointing out in the last paragraph of my previous post.

My usual advice is to just bite the bullet and invest the time it takes to understand how Python does package management and resolution really works, and how all the various devops approaches that are built on top of it work with it, so that you can make informed decisions and truly own your own stack.