But the part you miss is that it works. This is anecdotal for now but people are looking at evaluating that more objectively.

It's not even a stretch if you squint at this. The currently accepted treatment is SSRIs, the second S standing for serotonin. Psychedelics work on serotonin receptors. Why would it be surprising that if you tweak your serotonin receptors, you get treatment for depression? Again, this is not true of alcohol or cannabis.